Functional Analysis of Killer Ig-Like Receptor-Expressing Cytomegalovirus-Specific CD8+T Cells
نویسندگان
چکیده
منابع مشابه
Functional analysis of killer Ig-like receptor-expressing cytomegalovirus-specific CD8+ T cells.
Killer Ig-like receptors (KIR) are expressed by human NK cells and T cells. Although Ag-specific cytolytic activity and cytokine production of KIR(+) T cells can be inhibited by KIR ligation, the effect of KIR on proliferation is unclear. KIR(+) T cells have been reported to have a general proliferative defect. To investigate whether KIR(+) T cells represent end-stage dysfunctional T cells, we ...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.182.1.92